Before taking Tadalafil, it is important to understand the potential side effects and risks of the drug, especially if you have liver disease, kidney problems, or a history of prostate cancer.
Tadalafil is a medication that is used to treat erectile dysfunction. It is not a cure for ED, but it can improve sexual function and increase the risk of sexual dysfunction.
Tadalafil has not been approved by the FDA for the treatment of erectile dysfunction. The drug is approved for the treatment of erectile dysfunction only, and it may not be approved for the treatment of benign prostatic hyperplasia (BPH), which is a condition in which the prostate gland becomes enlarged.
If you have any questions about Tadalafil, please talk to your doctor or pharmacist.
Before taking Tadalafil, tell your doctor about all the medications you take, including prescription drugs, vitamins, and herbal supplements. Tadalafil can interact with other medications or drugs, so inform your doctor about all the medicines you take.
It is important to tell your doctor about all the products you use, including vitamins and herbal supplements. Tadalafil may lower blood pressure, especially if you have high blood pressure or if you are taking certain medications.
Tadalafil can cause serious side effects. If you experience any serious side effects, or if you have any side effects that bother you, call your doctor immediately.
Tadalafil is not for use in women. It may also not be used in women if the drug is not prescribed for women or if there is a history of breast cancer.
Tadalafil can interact with other medications or drugs, so inform your doctor about all the medications you take.
Tadalafil is not approved for use in women.
The FDA has approved tadalafil as a treatment for ED only in men. However, it is not approved for the treatment of BPH in women. Tadalafil can be used to treat erectile dysfunction if the drug is prescribed for women or if there is a history of breast cancer.
In some cases, it may also be used in patients with heart disease or if an underlying medical condition causes erectile dysfunction.
Take Tadalafil as directed by your doctor or pharmacist. Do not take Tadalafil more than once daily. It may be taken with or without food.
The dosage of Tadalafil is based on your medical condition and response to treatment. Your doctor will decide how much Tadalafil is safe for you to take based on your response to treatment. It is important not to exceed the recommended dose and to follow your doctor’s instructions carefully.
Tadalafil can cause side effects. If you have any side effects, such as headaches, dizziness, back pain, muscle aches, or flushing, talk to your doctor before taking Tadalafil. They may adjust your dosage or switch to a lower or lower-dose form of the medication if needed.
If you are taking another medication that contains tadalafil, talk with your doctor or pharmacist before taking it. This may affect how well Tadalafil works for you. Your doctor may also monitor you more frequently if you take tadalafil during pregnancy.
Tadalafil can interact with other medications, so inform your doctor about all the medications you take, including prescription drugs, vitamins, and herbal supplements. Tell any other healthcare professionals who are treating you that you are taking Tadalafil.
Erectile dysfunction (ED) is a common problem that affects men. It is often treated with medications, such as Viagra (sildenafil), Cialis (tadalafil), or Levitra (vardenafil). However, some men may also experience erectile dysfunction, especially if they have certain medical conditions.
There is no specific treatment for erectile dysfunction. However, men who have low testosterone levels may benefit from Tadalafil.
Consumer Medicine Information (CMI) summary
The on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist.
ADAPTUS contains the active ingredient tadalafil. It is used to treat erectile dysfunction, which is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Erectile dysfunction is a condition in which a man has difficulty achieving or maintaining an erection that is satisfactory for sexual activity. Tadalafil belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the muscles in the penis, thereby increasing blood flow into the penis when sexually aroused. This effect is beneficial for men with certain medical conditions. ADAPTUS is usually taken once or twice a day, depending on your doctor's advice. It should be taken on an as-needed basis, at least 30 minutes before sexual activity. It works by helping to improve blood flow to the penis, which can help to achieve and maintain an erection.
For more information, see Section
Do not use if you have ever had an allergic reaction to ADAPTUS or any of the ingredients listed at the end of the CMI.
Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.
Some medicines may interfere with ADAPTUS and affect how it works.
For more information, including whether any medicines are suitable, see Section
Things you should do | Remind any doctor, dentist or pharmacist you visit that you are using ADAPTUS. Tell any doctor, dentist or pharmacist you visit that you are using ADAPTUS. Keep all appointments with your doctor, as well as your pharmacist. Your doctor will likely check your progress regularly. |
|---|---|
Things you should not do | Do not give ADAPTUS to anyone else, even if they have the same condition as you. Do not take ADAPTUS to treat any other complaints unless your doctor says it will be safe to you. |
Driving or using machines | Do not drive or operate machinery until you know how ADAPTUS affects you. |
Looking after your medicine | Keep ADAPTUS in the original pack and dispose of any medicine that it may have. If you have any concerns about ADAPTUS, talk to your doctor or pharmacist. |
Like all medicines, ADAPTUS can have side effects.
ADAPTUS belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. PDE5 is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP causes relaxation of the smooth muscle in the penis, which allows blood to flow into the penis. This helps achieve and maintain an erection when sexually stimulated.
Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.
You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.
There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-
• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).
• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets
for chest pain or use Rectogesic ointment?
• Nicorandil (Ikorel), used to treat angina
• Cimetidine, used to treat stomach or duodenal (peptic) ulcers
• Theophylline, used to treat asthma
• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin
• Anti-fungals such as itraconazole and ketoconazole
• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone
• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide
• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat
• Recreational drugs:- amyl nitrate (poppers)
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.
Read more about… You may experience :- vomiting, gas, dizziness, light-headedness, … or a sudden loss of vision … … or a loss of hearing … … or a rash, itching, fever, chills, muscle aches, joint pain, joint problems, joint swelling, joint … or … or … or a swelling pain, pain, redness, fever, tingling, stuffy nose, … or a stuffy back, … or a full menstrual blood … … or swelling, pain, redness, fever, swelling, stuffy/dark- face or oral discharge … or … … or a severe decrease of kidney or liver function … or a severe liver failure, … or a very serious underlying health condition …
If you get any side effects or if you feel there is a problem that needs treatment just simply do not take Tadalafil and they will not improve your experience of how much you need to take the medicine.
How to take Tadalafil : You need to consult your GP before taking Tadalafil. You will be asked to state what treatment can’t be taken alongside Tadalafil and how much one treatment is safe for you to take. You should include: a full stomach, very high blood pressure or a heart condition. A family history of eye conditions such as retinitis or retinitis oculoasal (suddenly severe, eye pain can occur). You, or your child, is unlikely to be eligible for treatment if you are at high risk of serious eye problems because the eye ointment can be applied directly to the eye (photosensitivity). Tadalafil can cause a serious side effect if you are taking other medicines that:- Can also be used to treat certain cancers (e.g. users of doxazosin (Cardura]) can be switched to Tadalafil after use … … … or when needed (e.g. after a coronary procedure or after a stroke)You should not use Tadalafil if you have already taken this medicine and you have a history of severe cardiovascular problems or if you have a history of heart problems such as heart failure.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
ixieixieixieixieixieixieixieixieixieixieixieixie.com[ixie]ixie[/ixie]A. m. Henrie, J. n. Anderson, and J. off. Res. 2021;(11):2622.eprint⁴ Nawarskas. Tadalafil for Erectile Dysfunction.6. Aspen Healthcare Ltd.https://www.medicines.org.in/PMC463095/pills/bigfun-36.shtml
7. Aspen Healthcare Private Ltd.https://www.medicines.in/PMC463095/pills/bigfun-36.shtml
ixieixieixieixieixieixieixieixieixieixieixie.com[ixie]ixie[/ixie]R. A. Apere, A. C. Cunha, R. D. Chai, and S. M. Sood. Effects of tadalafil on cavernosal outgrowth and animal experimental data on pulmonary arterial hypertension: systematic review and meta-analysis.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630958.
ixieixieixieixieixieixieixieixieixie.com[ixie]ixie[/ixie]A. R Anderson. Bigfun-36 for Erectile Dysfunction.B. K.innamon. Ampicill C6.
K. Melbourne, M. Menarini, and F. Taylor. Tadalafil for erectile dysfunction.
Bailey. Erectile dysfunction and premature ejaculation.
E. Bailey, L. P. Campbell, S. Sayers, and R. Jones.
The aim of this study was to investigate the association of tadalafil and pde12-phosphohydrolase 1(PH1) polymorphisms with the risk of heart failure in Chinese patients with chronic renal failure. We evaluated the associations between the genotype of the polymorphism of PDE-1 (TGACTTCCTGGGTCAATG) and the polymorphism of PDE-1 (TCAGCTTCCGTCACTCG) with the risk of the CHD risk in an Asian population. A total of 119 cases and 101 controls were enrolled in this study. The frequencies of the polymorphisms of PDE-1 (TGACTTCCGTCAATG) and PDE-1 (TCAGCTTCCGTCAATG) were compared with the general population based information. The odds ratio (OR) and 95% confidence intervals (CIs) for CHD and CHD-related death in patients with TGACTTCCGTCAATG and PDE-1 polymorphisms were significantly increased by the TGACTTCCTGGGTCAATG genotype (P< 0.05) and the PDE-1 genotype (> 0.05). The OR of CHD risk of CHD in the TGACTTCCTGGGTCAATG genotype was significantly higher than that of CHD risk of CHD-related death in the TGACTTCCGTCAATG genotype (< 0.05). The OR of CHD risk of CHD in the TCAGCTTCCGTCACTCG genotype was significantly higher than that of the TCAGCTTCCGTCAATG genotype (The OR of CHD-related death in patients with TGACTTCCGTCAATG and PDE-1 polymorphisms was significantly higher than that of the TCAGCTTCCGTCAATG genotype (
Stade de France Pharmacy